منابع مشابه
Off-label prescribing: best practice or malpractice?
‘‘Labels’’ for medicines are also known as the ‘‘package inserts’’ that list the details of the approval granted by regulatory authorities such as the FDA (U.S. Food and Drug Administration) for the sale of medicines by the pharmaceutical industry. ‘‘Off-label’’ means utilizing an approved medicine in a manner not contained in the approved ‘‘label.’’ Although it is illegal for employees of the ...
متن کاملOff-label prescribing in older patients.
The practice of off-label prescribing, i.e. prescribing drugs either for unregistered/unapproved therapeutic indications and age groups or using unregistered/unapproved doses or methods of administration, is common in older patients. This may be due to the poor representation of this group in pre-marketing clinical trials assessing therapeutic efficacy and safety of novel therapies or merely to...
متن کاملOff-label prescribing in pediatric outpatients.
OBJECTIVE To study the characteristics of off-label prescribing and adverse drug reaction (ADR) occurrence in a sample of pediatric outpatients treated by general practitioners. METHODS A survey on pediatric drug prescribing was implemented in 46 general practices in southwestern France. All consecutive patients aged 0 to 16 years were included. Patient characteristics, reasons for consultati...
متن کاملOff-label prescribing for allergic diseases in children
The majority of drugs prescribed have not been tested in children and safety and efficacy of children's medicines are frequently supported by low quality of evidence. Therefore, a large percentage of prescriptions for children in the clinical daily practice are used off label. Despite the several recent legislation and regulatory efforts performed worldwide, they have not been successful in inc...
متن کاملClinical symptoms and 'off-label' prescribing in children with asthma.
A UK-wide database of structured asthma review consultations was used to investigate the prevalence of 'off-label' anti-asthma prescriptions in relationship to clinical symptoms of asthma control. The 1050 children (6.1%) aged 16 years or under issued with an off-label prescription reported more nighttime, daytime and activity asthma symptoms, and used more short-acting beta(2)-agonist medicati...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2013
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2013.075